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Figure 4 | Journal of Translational Medicine

Figure 4

From: Spatial organization of dendritic cells within tumor draining lymph nodes impacts clinical outcome in breast cancer patients

Figure 4

DCs in TDLNs are organized into smaller, less mature clusters compared to HLNs. (A) Number of DC clusters normalized to the total number of DCs in a node (relative number of DC clusters) (B) average size of a DC cluster in a node (calculated by taking an average of the number of DCs that make up individual DC clusters in a node) and (C) percentage of CD83 positive DCs of all clustered DCs in a node (% mature DCs out of all clustered DCs) were calculated in sections HLN (n=7), NSLN- (n=50) and NSLN+ (n=22). *denotes p<0.05, ** denotes p<0.01 and *** denotes p<0.001.

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