Figure 4

DCs in TDLNs are organized into smaller, less mature clusters compared to HLNs. (A) Number of DC clusters normalized to the total number of DCs in a node (relative number of DC clusters) (B) average size of a DC cluster in a node (calculated by taking an average of the number of DCs that make up individual DC clusters in a node) and (C) percentage of CD83 positive DCs of all clustered DCs in a node (% mature DCs out of all clustered DCs) were calculated in sections HLN (n=7), NSLN- (n=50) and NSLN+ (n=22). *denotes p<0.05, ** denotes p<0.01 and *** denotes p<0.001.