Figure 7From: Berberine protects human renal proximal tubular cells from hypoxia/reoxygenation injury via inhibiting endoplasmic reticulum and mitochondrial stress pathwaysSchematic diagram of the signal pathways involved in H/R-induced apoptosis in HK-2 cells. Proposed models represent that H/R induces HK-2 cell apoptosis through oxidative stress-regulated mitochondria-dependent and ER stress-triggered signaling cascades.Back to article page