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Table 2 Differentially expressed proteins (DEP) between cirrhotic HCV + and HCV+/HCC + compared to normal liver tissue samples of Caucasian Americans

From: Quantitative proteomic analysis in HCV-induced HCC reveals sets of proteins with potential significance for racial disparity

Protein ID Protein name Peptides % Coverage Mean iTRAQ ratios
     Normal HCV+/HCC- HCV+/HCC+
P00738 Haptoglobin 15 27 1.05 0.19 0.18
P11021 78 kDa glucose –regulated protein 12 23 1.15 0.45 0.18
P01834 Ig kappa chain C region 17 85 1.17 10.65 8.47
P67936 Tropomyosin alpha-4 chain 8 24 0.68 3.40 2.47
Q13011 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase 9 26 0.84 0.45 0.47
P62328 Thymosin beta-4 8 77 1.04 4.30 5.68
P05091 Aldehyde dehydrogenase 10 17 1.20 0.37 0.42
Q06278 Aldehyde oxidase 1 5 4 1.06 0.24 0.34
P26038 Moesin 7 15 0.83 2.20 2.02
P54868 Hydroxymethylglutaryl-CoA synthase 7 11 0.87 0.23 0.36
Q09666 Neuroblast differentiation-associated protein 6 5 0.93 3.03 2.78
P23284 Peptidyl-prolyl cis-trans isomerase B 3 13 0.90 0.48 0.37
P34896 Serine hydroxymethyltransferase 4 9 0.89 0.30 0.41
P0CG05 Ig lambda-2 chain C regions 3 35 1.07 20.96 12.90
Q05682 Caldesmon 3 6 0.76 11.04 7.29
P02647 Apolipoprotein A-I 3 10 1.35 2.79 3.51
P02787 Serotransferrin 2 3 1.24 6.71 6.30
P00505 Aspartate aminotransferase 2 4 0.86 0.37 0.44
P02741 C-reactive protein 2 3 0.80 0.15 0.13
P21333 Filamin A, alpha 1 1 0.86 4.15 4.38
P24752 Acetyl-CoA acetyltransferase 7 17 1.05 0.33 0.53
B9A064 Immunoglobulin lambda-like polypeptide 5 3 7 1.47 7.80 6.09
P12532 Creatine kinase B-type 1 6 1.25 8.21 5.36
P63313 Thymosin beta-10 3 64 1.01 2.86 2.46
P02753 Plasma retinol-binding protein 1 5 1.00 3.66 2.82
P01742 Ig heavy chain V-I region 2 10 0.91 5.77 7.12
341914926 PREDICTED: Ig heavy chain V-III region 1 16 1.18 2.89 2.40
Q16555 dihydropyrimidinase-related protein 2 isoform 1 2 3 1.50 3.91 3.02
P13716-2 Isoform 2 of Delta-aminolevulinic acid dehydratase 1 3 0.94 0.49 0.50
Q01995 Transgelin 1 5 1.04 5.20 4.34
P01701 Ig lambda chain V-I region 1 15 0.51 2.31 2.56
P18136 Ig kappa chain V-III region 1 14 1.08 2.22 3.51
  1. Note: Proteins shown in italics were validated using qRT-PCR or WB.