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Table 2 Differentially expressed proteins (DEP) between cirrhotic HCV + and HCV+/HCC + compared to normal liver tissue samples of Caucasian Americans

From: Quantitative proteomic analysis in HCV-induced HCC reveals sets of proteins with potential significance for racial disparity

Protein ID

Protein name

Peptides

% Coverage

Mean iTRAQ ratios

    

Normal

HCV+/HCC-

HCV+/HCC+

P00738

Haptoglobin

15

27

1.05

0.19

0.18

P11021

78 kDa glucose –regulated protein

12

23

1.15

0.45

0.18

P01834

Ig kappa chain C region

17

85

1.17

10.65

8.47

P67936

Tropomyosin alpha-4 chain

8

24

0.68

3.40

2.47

Q13011

Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase

9

26

0.84

0.45

0.47

P62328

Thymosin beta-4

8

77

1.04

4.30

5.68

P05091

Aldehyde dehydrogenase

10

17

1.20

0.37

0.42

Q06278

Aldehyde oxidase 1

5

4

1.06

0.24

0.34

P26038

Moesin

7

15

0.83

2.20

2.02

P54868

Hydroxymethylglutaryl-CoA synthase

7

11

0.87

0.23

0.36

Q09666

Neuroblast differentiation-associated protein

6

5

0.93

3.03

2.78

P23284

Peptidyl-prolyl cis-trans isomerase B

3

13

0.90

0.48

0.37

P34896

Serine hydroxymethyltransferase

4

9

0.89

0.30

0.41

P0CG05

Ig lambda-2 chain C regions

3

35

1.07

20.96

12.90

Q05682

Caldesmon

3

6

0.76

11.04

7.29

P02647

Apolipoprotein A-I

3

10

1.35

2.79

3.51

P02787

Serotransferrin

2

3

1.24

6.71

6.30

P00505

Aspartate aminotransferase

2

4

0.86

0.37

0.44

P02741

C-reactive protein

2

3

0.80

0.15

0.13

P21333

Filamin A, alpha

1

1

0.86

4.15

4.38

P24752

Acetyl-CoA acetyltransferase

7

17

1.05

0.33

0.53

B9A064

Immunoglobulin lambda-like polypeptide 5

3

7

1.47

7.80

6.09

P12532

Creatine kinase B-type

1

6

1.25

8.21

5.36

P63313

Thymosin beta-10

3

64

1.01

2.86

2.46

P02753

Plasma retinol-binding protein

1

5

1.00

3.66

2.82

P01742

Ig heavy chain V-I region

2

10

0.91

5.77

7.12

341914926

PREDICTED: Ig heavy chain V-III region

1

16

1.18

2.89

2.40

Q16555

dihydropyrimidinase-related protein 2 isoform 1

2

3

1.50

3.91

3.02

P13716-2

Isoform 2 of Delta-aminolevulinic acid dehydratase

1

3

0.94

0.49

0.50

Q01995

Transgelin

1

5

1.04

5.20

4.34

P01701

Ig lambda chain V-I region

1

15

0.51

2.31

2.56

P18136

Ig kappa chain V-III region

1

14

1.08

2.22

3.51

  1. Note: Proteins shown in italics were validated using qRT-PCR or WB.