Figure 5

Interactive Network representation of the cellular functions and pathways affected by thirty-two proteins that are commonly altered in Cirrhosis and HCC as compared to Normal. The network is enriched with proteins significantly linked to cell movement, connectivity tissue disorder and cancer. We used the Ingenuity Pathways Analysis tool (http://www.ingenuity.com) to generate the networks of proteins that are only differentially expressed in Cirrhosis and HCC as compared to normal. The intensity of the node color indicates the degree of up-regulation (red), down-regulation (green) or no effect (white) in HCC as compared to Normal samples.