Skip to main content

Advertisement

Table 2 Diagnostic values of established ions of peptide m/z 520.3 models and others

From: Serum dihydroxyacetone kinase peptide m/z 520.3 as predictor of disease severity in patients with compensated chronic hepatitis B

  S2-S4 versus S0-S1 S3-S4 versus S0-S2
  AUROC    95% CI Cut-off value Sensitivity Specificity AUROC    95% CI Cut-off value Sensitivity Specificity
520.3/176.1 0.915 0.855 0.976 1.401 0.886 0.902 0.924 0.936 0.948 1.287 0.868 0.98
520.3/353.7 0.892 0.818 0.967 0.161 0.829 0.922 0.825 0.855 0.929 0.129 0.732 0.919
520.3/459.8 0.724 0.617 0.832 0.368 0.629 0.725 0.797 0.692 0.902 0.337 0.692 0.902
520.3/503.3 0.891 0.824 0.957 12.751 0.851 0.865 0.92 0.916 0.965 9.050 0.862 0.979
520.3/351.3 0.871 0.793 0.949 43.85 0.882 0.852 0.849 0.954 1.000 28.91 0.745 0.954
520.3/593.1 0.908 0.842 0.974 1.769 0.829 0.903 0.804 0.795 0.947 1.487 0.71 0.899
FIB-4 0.793 0.7 0.885 222.70 0.757 0.801 0.801 0.705 0.896 408.77 0.836 0.645
Forn’s Index 0.811 0.715 0.906 -317.1 0.857 0.686 0.739 0.635 0.843 -416.01 0.673 0.742
APRI 0.685 0.573 0.798 33.79 0.771 0.643 0.697 0.577 0.816 59.94 0.655 0.677
  G2-G4 versus G0-G1 G3-G4 versus G0-G2
  AUROC    95% CI Cut-off value Sensitivity Specificity AUROC    95% CI Cut-off value Sensitivity Specificity
520.3/176.1 0.84 0.756 0.924 1.301 0.788 0.811 0.756 0.818 0.953 1.186 0.705 0.760
520.3/353.7 0.843 0.763 0.923 0.184 0.870 0.666 0.763 0.69 0.889 0.179 0.806 0.720
520.3/459.8 0.694 0.581 0.807 0.335 0.788 0.509 0.581 0.61 0.852 0.235 0.621 0.680
520.3/503.3 0.856 0.779 0.933 10.375 0.910 0.679 0.779 0.819 0.956 10.375 0.887 0.910
520.3/351.3 0.902 0.839 0.964 43.60 0.911 0.851 0.839 0.813 0.96 41.82 0.901 0.842
520.3/593.1 0.868 0.792 0.945 1.653 0.876 0.831 0.792 0.66 0.914 1.644 0.874 0.792