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Table 3 The general data in mice

From: Cardiac protective effects of irbesartan via the PPAR-gamma signaling pathway in angiotensin-converting enzyme 2-deficient mice

 

Ace2+/ycontrol

Ace2-/ycontrol

Ace2-/yIrbesartan

n

6

8

6

HR (bpm)

496 ± 11

494 ± 12

501 ± 10

BW (g)

26.53 ± 0.72

25.81 ± 0.61

26.68 ± 0.52

LVW (mg)

9.95 ± 0.38

12.18 ± 0.31*

10.35 ± 0.31

LVW/BW (mg/g)

0.37 ± 0.02

0.47 ± 0.03*

0.39 ± 0.02

LVEDD (mm)

3.83 ± 0.03

3.85 ± 0.03

3.86 ± 0.04

LVESD (mm)

1.75 ± 0.04

1.81 ± 0.04

1.79 ± 0.05

LVFS (%)

54.32 ± 0.93

53.05 ± 1.03

53.61 ± 1.14

LVEF (%)

62.03 ± 3.01

59.56 ± 2.37

63.83 ± 3.89

LVPWT (mm)

0.61 ± 0.03

0.78 ± 0.03*

0.65 ± 0.04

  1. HR heart rate; BW body weight; LVW left ventricular (LV) weight; LVEDD LV end diastolic diameter; LVESD LV end systolic diameter; LVFS LV fractional shortening; LVEF LV ejection fraction; LVPWT LV posterior wall thickness. n = 6-8. Results are presented as mean ± SEM. *, p < 0.05 compared with all other groups.