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Table 3 The general data in mice

From: Cardiac protective effects of irbesartan via the PPAR-gamma signaling pathway in angiotensin-converting enzyme 2-deficient mice

  Ace2+/ycontrol Ace2-/ycontrol Ace2-/yIrbesartan
n 6 8 6
HR (bpm) 496 ± 11 494 ± 12 501 ± 10
BW (g) 26.53 ± 0.72 25.81 ± 0.61 26.68 ± 0.52
LVW (mg) 9.95 ± 0.38 12.18 ± 0.31* 10.35 ± 0.31
LVW/BW (mg/g) 0.37 ± 0.02 0.47 ± 0.03* 0.39 ± 0.02
LVEDD (mm) 3.83 ± 0.03 3.85 ± 0.03 3.86 ± 0.04
LVESD (mm) 1.75 ± 0.04 1.81 ± 0.04 1.79 ± 0.05
LVFS (%) 54.32 ± 0.93 53.05 ± 1.03 53.61 ± 1.14
LVEF (%) 62.03 ± 3.01 59.56 ± 2.37 63.83 ± 3.89
LVPWT (mm) 0.61 ± 0.03 0.78 ± 0.03* 0.65 ± 0.04
  1. HR heart rate; BW body weight; LVW left ventricular (LV) weight; LVEDD LV end diastolic diameter; LVESD LV end systolic diameter; LVFS LV fractional shortening; LVEF LV ejection fraction; LVPWT LV posterior wall thickness. n = 6-8. Results are presented as mean ± SEM. *, p < 0.05 compared with all other groups.