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Table 5 Summary of genotypes-phenotypes for EDN1 SNPs that were classified based on Tmax values in all children

From: Genetic variance in Nitric Oxide Synthase and Endothelin Genes among children with and without Endothelial Dysfunction

Number of significant SNPs SNP Allele frequencies
1 EDN1 AA AG *GG *AA + AG GG + AG
  rs1476046(A/G) (n = 3) (n = 50) (n = 69) (n = 53) (n = 119)
  Tmax 37.13 ± 18.47 31.89 ± 19.20 *42.85 ± 20.62 *32.19 ± 19.03 38.25 ± 20.68
2 EDN1 CC CT *TT *CC + CT TT + CT
  rs4714384 (C/T) (n = 25) (n = 63) (n = 34) (n = 88) (n = 97)
  Tmax 37.08 ± 23.65 34.53 ± 17.56 *45.89 ± 21.82 *35.25 ± 19.38 38.51 ± 19.81
  1. *Indicates significant alleles.