Table 5 Summary of genotypes-phenotypes for EDN1 SNPs that were classified based on Tmax values in all children
Number of significant SNPs | SNP | Allele frequencies | ||||
|---|---|---|---|---|---|---|
1 | EDN1 | AA | AG | *GG | *AA + AG | GG + AG |
| Â | rs1476046(A/G) | (n = 3) | (n = 50) | (n = 69) | (n = 53) | (n = 119) |
|  | Tmax | 37.13 ± 18.47 | 31.89 ± 19.20 | *42.85 ± 20.62 | *32.19 ± 19.03 | 38.25 ± 20.68 |
2 | EDN1 | CC | CT | *TT | *CC + CT | TT + CT |
| Â | rs4714384 (C/T) | (n = 25) | (n = 63) | (n = 34) | (n = 88) | (n = 97) |
|  | Tmax | 37.08 ± 23.65 | 34.53 ± 17.56 | *45.89 ± 21.82 | *35.25 ± 19.38 | 38.51 ± 19.81 |