Genetic variance in Nitric Oxide Synthase and Endothelin Genes among children with and without Endothelial Dysfunction

Table 4 Distributions of allele and genotype frequencies for EDN1 SNPs in children with and without endothelial dysfunction

SNP	Allele	Endothelial function		Endothelial dysfunction		P- value	OR	CI 95%
SNP	Allele	n = 84		n = 38		P- value	OR	CI 95%
rs1476046	A/G	n	%	n	%
	AA	2	2	1	3	0.032	0.34	0.15-0.79
	AG	41	49	9	24
	GG	41	49	28	73
	Allele A	45	27	11	15
	Allele G	123	73	65	85
rs4714384	C/T	n	%	n	%
	CC	22	26	3	8	0.016	0.38	0.16-0.86
	CT	44	52	19	50
	TT	18	22	16	42
	Allele C	88	52	25	33
	Allele T	80	48	51	67

ISSN: 1479-5876