The mRNA expression of inflammatory mediators in post-transplant kidneys. The expression of IL-1β and IL-6, TNF-α, interferon (IFN)-α, IFN-β, IFN-γ, NF-κB and c-Jun detected by real-time qPCR was significantly increased in the caspase-3 siRNA preserved post-transplant kidneys (A-H). The data are expressed as 2−ΔΔ Ct normalized with β-actin relative to the normal kidneys of each group. Mean ± SEM, n = 5. *: P < 0.05; **: P < 0.01.