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Table 1 Baseline demographic and disease characteristics of patients with psoriasis

From: Modulation of cardiometabolic pathways in skin and serum from patients with psoriasis

Randomized patients, n

149

Age, years, Mean ± SD

46.3 ± 12.8

Sex

 

  Men, n (%)

114 (76.5)

White, n (%)

133 (89.3)

Psoriasis body surface area involvement, Mean ± SD

29.5 ± 18.6

Psoriasis Area and Severity Index (PASI) score, Mean ± SD

21.3 ± 9.0

Psoriatic arthritis, n (%)

38 (25.5)

Body Mass Index (BMI), n (%)

 

  N

148

  Normal (BMI <25)

29 (19.6)

  Overweight (BMI ≥25 and <30)

46 (31.1)

  Obese (BMI ≥30)

73 (49.3)

Metabolic Syndrome, n (%)a

41 (27.5)

Cigarette smoking, n (%)

 

  Current

50 (33.6)

  Past or current

97 (65.1)

Relevant medical history, n (%)

 

  ASCVDb

6 (4.0)

  Diabetes mellitus

21 (14.1)

  Hypertension

41 (27.5)

  Hyperlipidemia

31 (20.8)

  Family history of early ASCVD

15 (10.1)

High-density lipoprotein (HDL), n

141

  Mean ± SD

47.9 ± 12.9

  HDL <40 mg/dL, n (%)

43 (30.5)

Low-density lipoprotein, n

137

  Mean ± SD

113.1 ± 35.7

Triglycerides, n

141

  Median (IQ range)

134.0 (99.0, 182.0)

Total Cholesterol, n

141

  Mean ± SD

191.8 ± 40.0

Total Cholesterol/HDL, Mean ± SD

4.3 ± 1.4

  1. ASCVD atherosclerotic cardiovascular disease, IQ interquartile range.
  2. aMetabolic syndrome is defined using modified National Cholesterol Education Program criteria (waist circumference was replaced with BMI ≥ 30) including the presence of 3 or more of the 5 risk factors: BMI ≥ 30; fasting triglycerides ≥ 150 mg/dL; fasting HDL < 40 mg/dL (male) or HDL < 50 mg/dL (female); baseline systolic pressure ≥ 130 mmHg, baseline diastolic pressure ≥ 85 mmHg, or treatment for hypertension; fasting glucose ≥ 100 mg/dL
  3. bASCVD is defined as having a baseline medical history of myocardial infarction, coronary artery bypass, stroke, transient ischemic attack, or peripheral vascular disease