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Table 4 Univariate and multivariate analyses of various prognostic parameters in patients with breast cancer Cox-regression analysis (overall survival was modelled)

From: Flotillin-2 is associated with breast cancer progression and poor survival outcomes

  Univariate analysis Multivariate analysis
No. patients p Regression coefficient (SE) p Relative risk 95% confidence interval
FLOT2     0.002   
Low expression 89 <0.001 1.209(0.172)   Ref  
High expression 82    0.002 4.492 1.740-11.598
Clinical stage     <0.001   
I 21     Ref  
II 92 <0.001 1.618(0.314) 0.824 1.190 0.256-5.522
III 46    0.329 2.236 0.444-11.264
IV 12    0.014 8.594 1.545-47.790
ErbB-2     0.06   
0 42     Ref  
1 52 <0.001 0.376(0.106) 0.272 0.602 0.244-1.489
2 38    0.237 1.625 0.727-3.629
3 30    0.164 1.811 0.785-4.178
4 9    0.253 2.005 0.608-6.609
Histological differentiation     0.005   
Well 9 <0.001 1.283(0.262)   Ref  
Moderate 113    0.783 0.810 0.181-3.631
Poor 49    0.327 2.105 0.475-9.330