Skip to main content

Table 4 Univariate and multivariate analyses of various prognostic parameters in patients with breast cancer Cox-regression analysis (overall survival was modelled)

From: Flotillin-2 is associated with breast cancer progression and poor survival outcomes

 

Univariate analysis

Multivariate analysis

No. patients

p

Regression coefficient (SE)

p

Relative risk

95% confidence interval

FLOT2

   

0.002

  

Low expression

89

<0.001

1.209(0.172)

 

Ref

 

High expression

82

  

0.002

4.492

1.740-11.598

Clinical stage

   

<0.001

  

I

21

   

Ref

 

II

92

<0.001

1.618(0.314)

0.824

1.190

0.256-5.522

III

46

  

0.329

2.236

0.444-11.264

IV

12

  

0.014

8.594

1.545-47.790

ErbB-2

   

0.06

  

0

42

   

Ref

 

1

52

<0.001

0.376(0.106)

0.272

0.602

0.244-1.489

2

38

  

0.237

1.625

0.727-3.629

3

30

  

0.164

1.811

0.785-4.178

4

9

  

0.253

2.005

0.608-6.609

Histological differentiation

   

0.005

  

Well

9

<0.001

1.283(0.262)

 

Ref

 

Moderate

113

  

0.783

0.810

0.181-3.631

Poor

49

  

0.327

2.105

0.475-9.330