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Table 3 Frequencies of concomitant diseases in CF patients with different TNF-α and LT-α gene polymorphisms

From: TNF gene polymorphisms in cystic fibrosis patients: contribution to the disease progression

Genotype Asthma Tuberculosis Virus hepatitis
TNF-α308 GG 5.8% 5.0% 6.3%
(n = 145) (8/145) (7/140) (8/143)
TNF-α308GA 14.0% 2.9% 3.8%
(n = 53) (7/53) (2/51) (2/53)
P-value 0.068 0.94 0.9
LT-α + 252AA 6.5% 8.3% 6.4%
(n = 110) (7/110) (9/108) (7/109)
LT-α + 252GA 7.8% 0% 0%
(n = 67) (5/67) (0/65) (0/65)
LT-α + 252GG 10.0% 0% 16.7%
(n = 12) (1/12) (0/11) (1/12)
P value   PA/A,G/A = 0.013 PA/A,G/A = 0.035
   PA/A,G/G+G/A = 0.007 PA/A,G/G+G/A = 0.088