Figure 3

Multiple intravenous administrations of BM-MSCs suppressed macrophage infiltration in aortic tissues. A-I) Representative F4/80 immunofluorescence stained sections of suprarenal aortas from Sham, CONT, and MSC4 groups. Arrowheads indicated F4/80 macrophages. Scale bars=100 μm. J) Quantitation of F4/80- positive macrophages area as a ratio of the DAPI staining area. Data are presented as means ± SEM (n =10-12) **P<0.01, ***P<0.001 vs. group CONT, assessed by one-way ANOVA.