Table 2 Hematological toxicities ( n = 359 )
Low Dose (n = 60) | Total | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
|---|---|---|---|---|---|
Leukopenia | 13 (21.7%) | 5 (8.3%) | 6 (10%) | 2 (3.3%) | 0 (0%) |
Anemia | 33 (55.0%) | 24 (40%) | 9 (15%) | 0 (0%) | 0 (0%) |
Thrombocytopenia | 13 (21.7%) | 8 (13.3%) | 3 (5.0%) | 2 (3.3%) | 0 (0%) |
Intermediate Dose ( n = 77 ) | |||||
Leukopenia | 18 (23.4%) | 9 (11.7%) | 6 (7.8%) | 3 (3.9%) | 0 (0%) |
Anemia | 43 (55.8%) | 35 (45.5%) | 8 (10.4%) | 0 (0%) | 0 (0%) |
Thrombocytopenia | 23 (29.9%) | 20 (26.0%) | 2 (2.6%) | 1 (1.3%) | 0 (0%) |
High Dose ( n = 222 ) | |||||
Leukopenia | 77 (34.7%) | 31 (14.0%) | 31 (14.0%) | 13 (5.9%) | 2 (0.9%) |
Anemia | 145 (65.3%) | 117 (52.7%) | 22 (9.9%) | 5 (2.3%) | 0 (0%) |
Thrombocytopenia | 92 (41.4%) | 68 (30.6%) | 11 (5.0%) | 6 (2.7%) | 7 (3.2%) |