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Table 3 Patient samples and corresponding patient-derived NSCLC xenograft model information

From: Establishment of patient-derived non-small cell lung cancer xenograft models with genetic aberrations within EGFR, KRAS and FGFR1: useful tools for preclinical studies of targeted therapies

Model ID Patient NSCLC tissue implanted Patient derived LC xenograft models
  Pathology Mutation detection Gene amplification Mutation detection Gene amplification % TGI
   EGFR KRAS FGFR1 MET EGFR KRAS FGFR1 MET by Gefitinib
L004 AC WT WT None None WT WT None None 113
L023 SCC WT G12S None AMP WT G12S None AMP 0
L030 SCC WT Q61H None None WT Q61H None None 25
L104 SCC WT WT None None WT WT None None 46
L110 SCC WT WT None None WT WT None None 78
L115 SCC Exon19Del WT None None Exon19Del WT None None 199
L121 SCC WT WT AMP None WT WT AMP None 23
L123 SCC WT WT N/A None WT WT AMP None 47
L133 SCC WT WT AMP None WT WT AMP None N/A
L140 SCC WT WT None None WT WT None None N/A