Establishment of patient-derived non-small cell lung cancer xenograft models with genetic aberrations within EGFR, KRAS and FGFR1: useful tools for preclinical studies of targeted therapies

Table 2 Relationship of model establishment rate and patients’ clinical information

Patient information	Patient #	Derived model #	Established rate (%)	P value (univariate)	P value (multivariate)
Sex				0.0115	0.1896
Male	24	10	42
Female	7	0	0
Histologic type				0.0015	0.0218
SCC	15	9	60
AC	16	1	6
Pathologic stage				0.5017	n/a
Stage I	12	2	17
Stage II	7	3	43
Stage III/IV	11	4	36
Smoke status				0.0228	0.4631
Smoker	14	7	50
Non-smoker	16	2	12.5
Mutation				0.1031	n/a
EGFR	7	1	14
KRAS	3	2	67

ISSN: 1479-5876