Table 1 Distribution of secretoglobin mRNA expression in normal ovaries (NO) and epithelial ovarian cancers (EOC) and correlation with MGB2 gene expression *
Secretoglobin | % expressing | Relative mRNA expression | p value | Correlation with SCGB2A1 gene expression | |
|---|---|---|---|---|---|
Mean (SD) | |||||
| Â | Rho cc | p value | |||
SCGB2A1 (Mammaglobin B) | EOC 46/53 = 86.7% | 186883.54 (63045.00) | p < 0.001 | 1 | - |
NO 2/23 = 8.6% | 1432.00 (648.59) | ||||
SCGB2A2 (Mammaglobin A) | EOC 36/53 = 67.9% | 23295.42 (21171.01) | p < 0.001 | 0.63 | p < 0.001 |
NO 2/30 = 6.6% | 0.37 (0.33) | ||||
SCGB1D1 (Lipophilin A) | EOC 40/53 = 75.4% | 4741.58 (2680.96) | p < 0.001 | 0.66 | p < 0.001 |
NO 2/30 = 6.6% | 5.83 (4.19) | ||||
SCGB1D2 (Lipophilin B) | EOC 40/53 = 75.4% | 122631.77 (48990.82) | p < 0.001 | 0.77 | p < 0.001 |
NO 5/30 = 16.6% | 3818.80 (1908.12) | ||||
SCGB3A1 (HIN-1) | EOC 8/53 = 15.1% | 386,48 (1606,95) | p = 0.21 | 0.39 | p < 0.001 |
NO 3/30 = 10.0% | 2194.48 (6305.41) | ||||
SCGB1C1 (RYD5) | EOC 37/53 = 69.8% | 57.79(26.83) | p < 0.001 | 0.36 | p < 0.001 |
NO 3/30 = 10% | 2.70 (2.14) | ||||
SCGB1D4 (IIS) | EOC 29/53 = 54.7% | 72084.23 (69346.5) | p = 0.411 | 0.50 | p < 0.001 |
NO 10/26 = 38.4% | 340.77 (158.75) | ||||
SCGB1A1 (Uteroglobin) | EOC 11/53 = 20.7% | 138.72 (117.09) | p = 0.452 | 0.25 | p = 0.03 |
NO 5/30 = 16.6% | 185.43 (116.76) | ||||
SCGB3A2 (UGRP-1) | EOC 6/53 = 11.3% | 2.85 (1.65) | p = 0.190 | 0.16 | p = 0.17 |
NO 1/30 = 3.3% | 0.17 (0.16) | ||||