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Table 3 MicroRNAs differentially expressed in IR myocardium of canines with CPB and reperfusion by Microarray

From: The altered expression profile of microRNAs in cardiopulmonary bypass canine models and the effects of mir-499 on myocardial ischemic reperfusion injury

microRNA Control (T1)/reperfusion (T4)(signals) Fold change P value
cfa-miR-451 2239/548 0.24 1.07E-14
cfa-miR-1 10512/1379 0.13 1.09E-13
cfa-miR-423a 440/768 1.74 1.38E-10
cfa-miR-494 271/1914 2.82 2.80E-10
cfa-miR-489 791/386 7.06 2.05E-09
cfa-miR-214 382/632 1.65 2.37E-09
cfa-miR-574 318/1020 3.20 4.55E-09
cfa-miR-133c 3782/2612 0.69 1.19E-08
cfa-miR-143 1223/853 0.69 4.91E-08
cfa-miR-133b 3502/2515 0.71 3.64E-07
cfa-miR-23a 914/1467 1.60 3.94E-07
cfa-miR-30c 1436/823 0.57 1.40E-06
cfa-let-7e 518/981 1.89 2.90E-06
cfa-miR-23b 663/1197 1.80 5.52E-06
cfa-miR-499 1012/1296 1.28 8.70E-04
cfa-miR-191 964/831 0.86 1.41E-03
cfa-miR-30b 756/572 0.75 1.63E-03
cfa-miR-22 1732/1493 0.86 1.77E-03
cfa-miR-24 3381/3759 1.11 2.71E-03
  1. Microarray analysis showed that totally 19 microRNAs were altered, in which 10 microRNAs were down-regulated and 9 microRNAs were up-regulated.