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Table 3 MicroRNAs differentially expressed in IR myocardium of canines with CPB and reperfusion by Microarray

From: The altered expression profile of microRNAs in cardiopulmonary bypass canine models and the effects of mir-499 on myocardial ischemic reperfusion injury

microRNA

Control (T1)/reperfusion (T4)(signals)

Fold change

P value

cfa-miR-451

2239/548

0.24

1.07E-14

cfa-miR-1

10512/1379

0.13

1.09E-13

cfa-miR-423a

440/768

1.74

1.38E-10

cfa-miR-494

271/1914

2.82

2.80E-10

cfa-miR-489

791/386

7.06

2.05E-09

cfa-miR-214

382/632

1.65

2.37E-09

cfa-miR-574

318/1020

3.20

4.55E-09

cfa-miR-133c

3782/2612

0.69

1.19E-08

cfa-miR-143

1223/853

0.69

4.91E-08

cfa-miR-133b

3502/2515

0.71

3.64E-07

cfa-miR-23a

914/1467

1.60

3.94E-07

cfa-miR-30c

1436/823

0.57

1.40E-06

cfa-let-7e

518/981

1.89

2.90E-06

cfa-miR-23b

663/1197

1.80

5.52E-06

cfa-miR-499

1012/1296

1.28

8.70E-04

cfa-miR-191

964/831

0.86

1.41E-03

cfa-miR-30b

756/572

0.75

1.63E-03

cfa-miR-22

1732/1493

0.86

1.77E-03

cfa-miR-24

3381/3759

1.11

2.71E-03

  1. Microarray analysis showed that totally 19 microRNAs were altered, in which 10 microRNAs were down-regulated and 9 microRNAs were up-regulated.