Variables | N | N of death (%) | Median OS (Range) | 5-year survival rate (%) | Log-rank test χ2value | P |
---|---|---|---|---|---|---|
Age (yrs) | ||||||
<60 | 99 | 52 (52.5) | 30.1 (1.5-99.5) | 45.1 | 3.584 | 0.058 |
≥60 | 85 | 56 (65.9) | 24.8 (0.8-102.3) | 28.6 | ||
Gender | ||||||
Male | 132 | 74 (56.1) | 30.3 (0.8-102.3) | 40.0 | 2.114 | 0.146 |
Female | 52 | 34 (65.4) | 25.1 (1.3-94.8) | 30.3 | ||
Tumor size (cm2) a | ||||||
<16 | 73 | 35 (47.9) | 41.6 (1.1-99.5) | 52.9 | 7.882 | 0.005 |
≥16 | 88 | 57 (64.8) | 24.2 (0.8-102.3) | 29.2 | ||
Histological grade b | ||||||
1/2 | 55 | 88 (56.1) | 30.1 (1.1-102.3) | 54.2 | 13.412 | <0.001 |
3/4 | 124 | 20 (74.1) | 16.8 (0.8-74.9) | 30.1 | ||
Lymph nodes metastasis | ||||||
Yes | 131 | 83 (63.4) | 24.8 (0.8-102.3) | 52.9 | 5.895 | 0.015 |
No | 53 | 25 (47.2) | 34.1 (6.1-99.5) | 30.5 | ||
Serosa invasion (T stage) | ||||||
T1-2 | 27 | 7 (25.9) | 58.9 (20.2-99.5) | 74.9 | 14.742 | <0.001 |
T3-4 | 157 | 101 (64.3) | 24.8 (0.8-102.3) | 30.8 | ||
TNM | ||||||
Early (I, II) | 58 | 26 (44.8) | 35.8 (6.1-99.5) | 54.0 | 9.823 | 0.002 |
Advanced | 126 | 82 (65.1) | 22.8 (0.8-102.3) | 29.2 | ||
(III, IV) | ||||||
Surgery | ||||||
SR | 159 | 89 (56.0) | 30.0 (0.8-102.3) | 39.8 | 5.902 | 0.015 |
TR/CR | 25 | 19 (76.0) | 18.0 (3.8-89.9) | 21.8 | ||
Chemotherapy | ||||||
Yes | 149 | 87 (49.7) | 33.5 (5.3-99.5) | 35.9 | 0.016 | 0.900 |
No | 35 | 21 (60.0) | 28.4 (0.8-102.3) | 40.0 | ||
LNR c | ||||||
≤0.33 | 94 | 41 (43.6) | 38.8 (1.1-102.3) | 55.1 | 24.881 | <0.001 |
>0.33 | 90 | 67 (74.4) | 20.1 (0.8-99.1) | 18.3 | ||
MT1-MMP | ||||||
Negative | 46 | 18 (39.1) | 35.7 (3.8-79.3) | 54.0 | 5.869 | 0.015 |
Positive | 138 | 90 (65.2) | 25.4 (0.8-102.3) | 32.2 | ||
CD11b + immunocytes density | ||||||
Low | 92 | 62 (67.4) | 25.1 (0.8-99.1) | 27.6 | 4.655 | 0.031 |
High | 92 | 46 (50.0) | 30.7 (1.3-102.3) | 46.7 | ||
Combined features (MT1-MMP density, CD11b + immunocytes density and LNR) | ||||||
Group I | 73 | 26 (35.6) | 38.7 (6.1-94.1) | 61.4 | 28.173 | <0.001 |
Group II | 111 | 82 (73.9) | 18.1 (0.8-90.9) | 21.1 |