Table 2 The relationship between MT1-MMP, CD11b + immunocytes density and cinico-pathological features
Variables | MT1-MMP expression | CD11b + immunocytes density | ||||
|---|---|---|---|---|---|---|
Negative (n = 46) | Positive (n = 138) | P | Low (n = 92) | High (n = 92) | P | |
N (%) | N (%) | N (%) | N (%) | |||
Age (yrs) | ||||||
<60 | 26 (56.5) | 20 (43.5) | 0.669 | 43 (43.4) | 56 (56.6) | 0.055 |
≥60 | 73 (52.9) | 65 (47.1) | 49 (57.6) | 36 (42.4) | ||
Gender | ||||||
Male | 33 (25.0) | 99 (75.0) | 1.000 | 66 (50.0) | 66 (50.0) | 1.000 |
Female | 13 (25.0) | 39 (75.0) | 26 (50.0) | 26 (50.0) | ||
Tumor size (cm2) a | ||||||
<16 | 12 (16.4) | 61 (83.6) | 0.007 | 35 (47.9) | 38 (52.1) | 0.404 |
≥16 | 31 (35.2) | 57 (64.8) | 48 (54.5) | 40 (45.5) | ||
Location | ||||||
Distal | 18 (18.4) | 80 (81.6) | 0.027 | 51 (52.0) | 47 (48.0) | 0.555 |
Non-distal | 28 (32.6) | 58 (67.4) | 41 (47.7) | 45 (52.3) | ||
Histological grade b | ||||||
1/2 | 13 (23.6) | 42 (76.4) | 0.845 | 24 (43.6) | 31(56.4) | 0.376 |
3/4 | 31 (25.0) | 93 (75.0) | 63 (50.8) | 61 (49.2) | ||
Lymph node metastasis | ||||||
Yes | 31 (23.7) | 100 (76.3) | 0.511 | 73 (55.7) | 58 (44.3) | 0.015 |
No | 15 (28.3) | 38 (71.7) | 19 (35.8) | 34 (64.2) | ||
LNR c | ||||||
≤0.33 | 27 (28.7) | 67 (71.3) | 0.233 | 39 (41.5) | 55 (58.5) | 0.018 |
>0.33 | 19 (21.1) | 71 (78.9) | 53 (58.9) | 37 (41.1) | ||
Serosa invasion (T stage) | ||||||
T1-2 | 4 (14.8) | 23 (85.2) | 0.186 | 10 (37.0) | 17 (63.0) | 0.145 |
T3-4 | 42 (26.8) | 115 (73.2) | 82 (52.2) | 75 (47.8) | ||
TNM staging | ||||||
Early (I, II) | 13 (22.4) | 45 (77.6) | 0.583 | 21 (36.2) | 37 (63.8) | 0.011 |
Advanced (III, IV) | 33 (26.2) | 93 (73.8) | 71 (56.3) | 55 (43.7) | ||
Recurrence | ||||||
Yes | 9 (15.0) | 51 (85.0) | 0.029 | 30 (50.0) | 30 (50.0) | 1.000 |
No | 37 (29.8) | 87 (70.2) | 62 (50.0) | 62 (50.0) | ||
Recurrence location d | ||||||
Local-regional | 7 (18.9) | 30 (81.1) | 0.460 | 20 (54.1) | 17 (45.9) | 0.426 |
Distant | 2 (8.7) | 21 (91.3) | 10 (43.5) | 13 (56.5) | ||