Table 3 Criteria for haploidentical PBSC donation
From: Cellular immunotherapy for refractory hematological malignancies
Donor eligibility criteria | |
|---|---|
Inclusion criteria | Biological family members |
3/6 HLA match (using loci A, B, DR) | |
18 years of age | |
No malignancy in the past 5 years except for non-melanoma skin cancers | |
Normal CBC | |
β-HCG urine or serum negative if donor is of childbearing age | |
Adequate venous access so leukapheresis can be performed via standard peripheral IV | |
Exclusion criteria | HIV-1 or 2, syphilis, hepatitis B or C, HTLV 1 or 2, CMV, Chagas, and West Nile Virus positive |
Symptomatic congestive heart failure (CHF) | |
Oxygen dependant chronic obstructive lung disease (COPD) | |
Cirrhosis or active liver disease | |
History of any lymphoid, myeloid or other non-solid malignancy | |
History of transplantation |