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Table 3 Criteria for haploidentical PBSC donation

From: Cellular immunotherapy for refractory hematological malignancies

Donor eligibility criteria


Inclusion criteria

Biological family members


3/6 HLA match (using loci A, B, DR)


18 years of age


No malignancy in the past 5 years except for non-melanoma skin cancers


Normal CBC


β-HCG urine or serum negative if donor is of childbearing age


Adequate venous access so leukapheresis can be performed via standard peripheral IV

Exclusion criteria

HIV-1 or 2, syphilis, hepatitis B or C, HTLV 1 or 2, CMV, Chagas, and West Nile Virus positive


Symptomatic congestive heart failure (CHF)


Oxygen dependant chronic obstructive lung disease (COPD)


Cirrhosis or active liver disease


History of any lymphoid, myeloid or other non-solid malignancy


History of transplantation