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Table 2 The peptides of C3 and A2M were identified by iTRAQ analysis

From: Complementary serum proteomic analysis of autoimmune hepatitis in mice and patients

Protein name Peptide sequence Ion scorea Peptide ratio (116/114)b Protein ratio (116/114)c
alpha-2-macroglobulin AIGYLNTGYQR. 43 1.708 1.61 ± 0.14
GVPIPNK. 19 1.496  
SASNMAIVDVK. 75 1.727
SIYKPGQTVK. 48 1.401
ALLAYAFALAGNQDKR. 77 1.499
complement C3d LVAYYTLIGASGQR 77 2.9 2.19 ± 0.78
AGDFLEANYMNLQR 48 1.363
YFKPGMPFDLMVFVTNPDGSPAYR 45 1.385
DQLTCNK 42 1.316
TGLQEVEVK 54 1.932
  1. aProbability-based Mascot scores.
  2. bThe peptides of C3 and A2M were identified by iTRAQ analysis (Control: 114; AIH: 116).
  3. cThe differential expression of C3 and A2M in serum between AIH patients and controls was calculated based on the isotope labeling peptides.
  4. d Peptide “531LVAYYTLIGASGQR544” is a part of C3β chain.
  5. Peptide “1172AGDFLEANYMNLQR1185” is a part of C3d fragment.
  6. Peptide “363YFKPGMPFDLMVFVTNPDGSPAYR386” is a part of C3β chain.
  7. Peptide “1354DQLTCNK1360” is a part of C3c α chain fragment 2.
  8. Peptide “905TGLQEVEVK913” is a part of C3c α chain fragment 1.