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Table 3 Univariate and multivariate analysis for clinicopathologic variables

From: Nuclear β-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer

  Univariate analysis Multivariate analysis
Parameters HRa 95% CIb P c HRa 95% CIb P c
Gender       
Male vs. female 1.032 0.782-1.363 0.826    
Age (years)       
<52 vs.≥52 0.995 0.756-1.311 0.948    
Histologic subtype       
ad vs l 1.111 0.842-1.466 0.456    
T classification       
T1–T2 vs. T3–T4 0.956 0.832-1.099 0.529    
C classification       
I-II vs. III 0.961 0.818-1.129 0.629    
Differention       
Grade1,Grade2,Grade3 1.520 1.272-1.816 0.000 1.526 1.273-1.829 0.000
Membranous       
positive and negative 0.763 0.571-1.021 0.069 0.820 0.609-1.106 0.193
Cytoplasmic       
positive and negative 1.815 1.375-2.396 0.000 1.871 1.412-2.478 0.000
Nuclear       
positive and negative 3.864 2.872-5.200 0.000 3.776 2.786-5.118 0.000
Nanog       
positive and negative 1.994 1.494-2.661 0.000 1.700 1.249-2.315 0.001
  1. a HR Harzard Rate.
  2. b CI Confidence Interval.
  3. c Cox regression model.
  4. The expression levels of cytoplasmic and nuclear β-catenin and Nanog were an independent prognosticator for overall survive.
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