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Table 3 Univariate and multivariate analysis for clinicopathologic variables

From: Nuclear β-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer

 

Univariate analysis

Multivariate analysis

Parameters

HRa

95% CIb

P c

HRa

95% CIb

P c

Gender

      

Male vs. female

1.032

0.782-1.363

0.826

   

Age (years)

      

<52 vs.≥52

0.995

0.756-1.311

0.948

   

Histologic subtype

      

ad vs l

1.111

0.842-1.466

0.456

   

T classification

      

T1–T2 vs. T3–T4

0.956

0.832-1.099

0.529

   

C classification

      

I-II vs. III

0.961

0.818-1.129

0.629

   

Differention

      

Grade1,Grade2,Grade3

1.520

1.272-1.816

0.000

1.526

1.273-1.829

0.000

Membranous

      

positive and negative

0.763

0.571-1.021

0.069

0.820

0.609-1.106

0.193

Cytoplasmic

      

positive and negative

1.815

1.375-2.396

0.000

1.871

1.412-2.478

0.000

Nuclear

      

positive and negative

3.864

2.872-5.200

0.000

3.776

2.786-5.118

0.000

Nanog

      

positive and negative

1.994

1.494-2.661

0.000

1.700

1.249-2.315

0.001

  1. a HR Harzard Rate.
  2. b CI Confidence Interval.
  3. c Cox regression model.
  4. The expression levels of cytoplasmic and nuclear β-catenin and Nanog were an independent prognosticator for overall survive.