Figure 6

Overexpression of SATB1 promotes the invasion and growth of LNCaP cells. A-D: The invasion of LNCaP cells was measured by Transwell chamber. A, LNCaP cells untransfected. B, LNCaP cells transfected with pcDNA3.1. C, LNCaP cells transfected with pcDNA3.1-SATB1. Magnification: 200×. D: Quantitative analysis of the number of invaded cells as shown in A-C (n = 3). *P < 0.05 compared to cells transfected with pcDNA3.1. E: The proliferation of LNCaP cells was determined by CCK8 assay (n = 3). The cell proliferation ratio was calculated for LNCaP cells at 24 h, 48 h and 72 h after transfection of pcDNA3.1 or pcDNA3.1-SATB1. *P < 0.05 compared to corresponding cells transfected with pcDNA3.1.