Figure 4

Silencing of SATB1 inhibits the invasion and growth of DU-145 cells. A-D: The invasion of DU-145 cells was measured by Transwell chamber. A, DU-145 cells untransfected. B, DU-145 cells transfected with pSliencer3.1. C, DU-145 cells transfected with pSilencer3.1-SATB1. Magnification: 200×. D: Quantitative analysis of the number of invaded cells as shown in A-C (n = 3). E: The proliferation of DU-145 cells was determined by CCK8 assay (n = 3). The cell proliferation inhibition rate was calculated for DU-145 cells at 24 h, 48 h and 72 h after transfection with pSilencer3.1-SATB1. *P < 0.05 compared to cells transfected with pSliencer3.1.