Table 5 Protein expression (Mean ± SD) of various cytokines in patient and control groups as measured by ELISA
Cytokines | Control subjects (N = 850) | Periodontitis patients (N = 440) | p value | Detection Range pg/ml |
|---|---|---|---|---|
IL-1α | 24.08 ( ± 4.62) | 59.73 ( ± 11.36) | 0.0008 | 31.25 - 1000 |
IL-1β | 19.57 ( ± 3.75) | 78.07 ( ± 17.09) | 0.0004 | 15.6 - 500 |
IL-6 | 27.35 ( ± 2.87) | 92.94 ( ± 17.44) | 0.0005 | 2 - 200 |
TNF-α | 26.90 ( ± 4.55) | 67.61 ( ± 14.60) | 0.0002 | 8 - 800 |
IFN-γ | 52.77 ( ± 8.12) | 94.71 ( ± 9.90) | 0.0003 | 5 - 400 |
IL-4 | 1.16 ( ± 0.20) | 4.62 ( ± 0.58) | 0.0003 | 0.7 - 35 |
IL-10 | 22.70 ( ± 3.41) | 46.89 ( ± 5.85) | 0.0012 | 5 - 400 |