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Table 3 Correlations between Pathologic Response and Clinicopathological Characteristics in Patients with TNBCs

From: Overexpression of epithelial growth factor receptor (EGFR) predicts better response to neo-adjuvant chemotherapy in patients with triple-negative breast cancer

Factors

pCR

RD

OR‡

P*

P#

 

No. of Patients

No. of Patients

(95% CI†)

  

Age, years

     

≤35

0

0

/

/

/

>35

10

30

/

  

Menstrual Status

     

Postmenopause

2

14

0.38

0.263

1.000

Premenopause

8

16

(0.09 - 1.54)

  

Histology

     

Ductal

10

28

1.62

1.000

1.000

Nonductal

0

2

(0.12 - 21.37)

  

Prechemotherapy N stage

     

N0

6

20

0.81

0.718

1.000

N1- N3

4

10

(0.27 - 2.39)

  

Histological grade

     

I - II

6

12

1.83

0.300

1.000

III

4

18

(0.61- 5.51)

  

EGFR

     

Positive

10

0

59.18

< 0.001

0.714

Negative

0

30

(3.77- 927.97)

  
  1. Table notes:
  2. ‡OR: odds ratio
  3. †CI: confidence interval
  4. *Determined by logistic analysis
  5. #Determined by multivariate analysis