Table 2 Molecular subtype distrubutions of 169 Han Chinese breast cancers with different intrinsic genes and adjustment
Intrinsic genes | Original data without adjustment | Mean-centring of genes | DWD adjustment |
|---|---|---|---|
Sørlie 500 | |||
Luminal A | 36 | 69 | 70 |
Luminal B | 60 | 24 | 23 |
Normal breast-like | 4 | 11 | 15 |
Basal-like | 37 | 37 | 44 |
HER2-enriched | 2 | 21 | 13 |
Unclassified | 30 | 7 | 4 |
Hu 306 | |||
Luminal A | 84 | 58 | 57 |
Luminal B | 1 | 32 | 35 |
Normal breast-like | 0 | 8 | 10 |
Basal-like | 30 | 41 | 41 |
HER2-enriched | 16 | 29 | 25 |
Unclassified | 38 | 1 | 1 |
PAM50 | |||
Luminal A | 70 | 56 | 51 |
Luminal B | 32 | 36 | 19 |
Normal breast-like | 10 | 6 | 27 |
Basal-like | 36 | 41 | 41 |
HER2-enriched | 19 | 30 | 31 |
Unclassified | 2 | 0 | 0 |