Figure 7

Laser Doppler scanning of hind limb blood flow on day 14 after CLI induction (n = 9). A to C & D) Normal blood flow in both hind limbs in normal control (A), obesity (B) and obesity control (C) prior to the procedure. E to G) Significantly reduced ratio of ischemic/normal blood flow (INBF) in obesity (F) group than in obesity control (G) and normal control (E) groups, and notably lower in obesity control group than in normal controls by day 14 after CLI procedure. H) * vs. other groups with different symbols, p < 0.001. Statistical analysis by ANOVA followed by Bonferroni multiple comparison post hoc test.