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Table 2 Genotype and haplotype frequencies of SLCO polymorphisms in 53 postmenopausal patients with osteoporosis

From: Organic anion transporting polypeptides OATP1B1 and OATP1B3 and their genetic variants influence the pharmacokinetics and pharmacodynamics of raloxifene

SLCO variant genotype number of patients frequency (%)
SLCO1B1 c.388A > G AA 14 26.4
  AG 28 52.8
  GG 11 20.8
SLCO1B1 c.521T > C TT 35 66.0
  TC 18 34.0
  CC 0 0
SLCO1B3 int7C > G CC 36 67.9
  CG 16 30.2
  GG 1 1.9
SLCO1B1 haplotype number haplotype copies   
*1a (reference haplotype) 0 11 20.8
  1 30 56.6
  2 12 22.6
*1b (c.388A > G) 0 24 45.3
  1 24 45.3
  2 5 9.4
*5 (c.521T > C) 0 51 96.2
  1 2 3.8
  2 0 0
*15 (c.388A > G and c.521T > C) 0 37 69.8
  1 16 30.2
  2 0 0