Gene expression profiling after dose standardization of SNP. A) Serum Nitrite concentration (μM). Values are mean ± SEM; n = 6. *P < 0.05 for SNP 100 mM vs. control; #P < 0.05 for SNP 100 mM vs. SNP 50 mM. B) mRNA expression after 4 weeks of treatment showed significantly reduced expression of α-SMA, collagen1α1, TIMP1 and NF-кB compared to CCl4 group. On the other hand, Albumin mRNA expression showed significant improvement after SNP-MSCs treatment. P-value < 0.05 was considered significant n = 3.*P < 0.05 for SNP-MSCs vs. CCl4; #P < 0.05 for SNP-MSCs vs. MSCs; φP < 0.05 for SNP-MSCs vs. SNP. C) Expression (%) of SMA+/TUNEL + cells in all groups indicating HSC apoptosis after SNP administration. ***P < 0.001 for SNP vs. CCl4; ###P < 0.001 for SNP-MSCs vs. CCl4.