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Table 1 TH1:TH2 index for p24 and gp140

From: Effects of adjuvants on IgG subclasses elicited by virus-like Particles

p24

VLP

VLP+ODN1826

VLP+poly(I:C)

IgG1 (T H 2)

300

300

900

IgG2a (T H 1)

100

900

8,100

IgG3 (T H 1)

300

300

2,700

T H 1:T H 2 index

0.66

2

6

gp140

VLP

VLP+ODN1826

VLP+poly(I:C)

IgG1 (T H 2)

900

900

900

IgG2a (T H 1)

100

900

2,700

IgG3 (T H 1)

300

300

900

T H 1:T H 2 index

0.22

0.66

2

  1. The index has been calculated as described in Materials and Methods section. Index < 1 = TH2 polarization. Index > 1 = TH1 polarization.