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Table 3 Patient characteristics and results of survival analysis for primary glioblastoma patients when stratified by MGMT methylation status

From: MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR

Overall survival

 

MGMT methylation status

 

Total

qMSP

Pyrosequencing

  

Methylated

Unmethylated

Methylated

Unmethylated

Patients (n)

58

19

39

29

29

Male/Female

31/27

10/9

21/18

15/14

16/13

Mean agea

(Standard deviation)

58.5

(9.1)

57.5

(8.7)

59.0

(9.3)

59.3

(8.5)

57.7

(9.7)

Median survivalb

(Standard error)

13.1

(1.1)

17.6

(4.2)

12.2

(1.0)

16.1

(3.7)

11.5

(0.4)

2-years overall survival (%)

(Standard error)

21.8

(0.06)

35.5

(0.11)

15.4

(0.06)

33.6

(0.09)

10.3

(0.06)

  1. a)Years; b) Months