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Figure 7 | Journal of Translational Medicine

Figure 7

From: Congruence as a measurement of extended haplotype structure across the genome

Figure 7

Comparing unrelated HapMap populations: chromosome 10. This figure shows rolling congruence over a section of chromosome 10. Detailed linkage disequilibrium (LD) plots with haplotype blocks and allele identity plots correspond to the shaded peak. The two horizontal reference lines on the rolling congruence plot correspond to the 99th percentile of congruence observations across the genome. That value is 51.1% for CEU (solid line) and 27.5% for YRI (dotted line). On the LD plots, shades of red indicate increasing D'. For the allele identity plots, each column is one chromosome (as represented by 418 SNPs and 1.11 Mb) and each row is a SNP. Yellow represents alleles that match the consensus sequence whereas blue represents alleles that do not match the consensus. Congruent chromosomes are indicated by the tick mark at the bottom of the allele identity plot. This peak on chromosome 10 (near 103 Mb) demonstrates high YRI congruence but lower CEU congruence

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