Table 2 Associations between SPARC expression and clinicopathologic characteristics among all NPC cases
SPARC expression | ||||
|---|---|---|---|---|
Characteristics | Low (n = 701) (%) | High (n = 392) (%) | r | P -value |
Age* (years) | Â | Â | Â | Â |
≤ 47 | 366 (52.5) | 202 (52.1) |  |  |
> 47 | 331 (47.5) | 186 (47.9) | 0.004 | 0.887 |
Sex | Â | Â | Â | Â |
Female | 209 (29.8) | 109 (27.8) | Â | Â |
Male | 492 (70.2) | 283 (72.2) | 0.021 | 0.483 |
Clinical stage | Â | Â | Â | Â |
I + II | 215 (30.8) | 100 (25.6) | Â | Â |
III + IV | 482 (69.2) | 291 (74.4) | 0.056 | 0.066 |
Relapse | Â | Â | Â | Â |
No | 649 (92.7) | 352 (89.8) | Â | Â |
Yes | 51 (7.3) | 40 (10.2) | 0.051 | 0.094 |
Metastasis | Â | Â | Â | Â |
No | 647 (92.4) | 337 (86.0) | Â | Â |
Yes | 53 (7.6) | 55 (14.0) | 0.104 | 0.001 |
WHO histological classification | Â | Â | Â | Â |
NKUC | 566 (80.9) | 287 (73.8) | Â | Â |
NKDC | 118 (16.9) | 88 (22.6) | Â | Â |
KSCC | 16 (2.2) | 14 (3.6) | 0.082 | 0.023 |