Skip to main content

Table 2 Associations between SPARC expression and clinicopathologic characteristics among all NPC cases

From: Secreted protein acidic and rich in cysteine (SPARC) is associated with nasopharyngeal carcinoma metastasis and poor prognosis

SPARC expression
Characteristics Low
(n = 701) (%)
High
(n = 392) (%)
r P -value
Age* (years)     
≤ 47 366 (52.5) 202 (52.1)   
> 47 331 (47.5) 186 (47.9) 0.004 0.887
Sex     
Female 209 (29.8) 109 (27.8)   
Male 492 (70.2) 283 (72.2) 0.021 0.483
Clinical stage     
I + II 215 (30.8) 100 (25.6)   
III + IV 482 (69.2) 291 (74.4) 0.056 0.066
Relapse     
No 649 (92.7) 352 (89.8)   
Yes 51 (7.3) 40 (10.2) 0.051 0.094
Metastasis     
No 647 (92.4) 337 (86.0)   
Yes 53 (7.6) 55 (14.0) 0.104 0.001
WHO histological classification     
NKUC 566 (80.9) 287 (73.8)   
NKDC 118 (16.9) 88 (22.6)   
KSCC 16 (2.2) 14 (3.6) 0.082 0.023
  1. *Median age; SPARC secreted protein acidic and rich in cysteine; NPC nasopharyngeal carcinoma; WHO World Health Organization; NKUC nonkeratinized undifferentiated carcinoma; NKDC nonkeratinized differentiated carcinoma; KSCC keratinized squamous cell carcinoma