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Table 1 Flow cytometric analysis of H-ADMSC and A-ADMSC surface markers following Day-14 cell culture

From: Impact of apoptotic adipose-derived mesenchymal stem cells on attenuating organ damage and reducing mortality in Rat sepsis syndrome induced by cecal puncture and ligation

Stem cell surface markers H-ADMSC A-ADMSC* p-value
 CD31+ 4.4 ± 1.9 3.1 ± 2.2 0.871
 CD34+ 12.6 ± 5.6 11.2 ± 5.9 0.729
 VEGF+ 29.2 ± 8.9 15.9 ± 5.7 0.027
 CD45+ 13.7 ± 4.3 6.0 ± 3.3 0.022
 C-kit+ 14.3 ± 4.9 8.9 ± 2.8 0.028
 Sca-1+ 1.9 ± 0.7 1.6 ± 0.9 0.454
 CD133+ 8.6 ± 4.2 5.7 ± 3.4 0.312
 CD90+ 92.4 ± 3.7 81.4 ± 2.9 0.029
 CD271+ 28.3 ± 4.2 10.1 ± 2.9 0.004
Early apoptosis (annexin V+/PI-) 1.03 ± 1.17 10.48 ± 3.67 <0.0001
Late apoptosis (annexin V+/PI+) 4.27 ± 0.59 18.18 ± 4.75 <0.0001
  1. Data are expressed as %.
  2. n = 8 in each experimental study.
  3. H = healthy; A = apoptosis; ADMSC = adipose-derived mesenchymal stem cell; VEGF = vascular endothelial growth factor.
  4. * An additional 96 hour serum-deprived cell culture was performed for A-ADMSCs.