Figure 7From: Impact of apoptotic adipose-derived mesenchymal stem cells on attenuating organ damage and reducing mortality in Rat sepsis syndrome induced by cecal puncture and ligationProtein expressions of inflammatory and oxidative stress biomarkers of left ventricular myocardium at 72 h after CLP / SP. A, B and C) The protein expressions of tumor necrotic factor (TNF)-α (A), matrix metalloproteinase (MMP)-9 (B) and nuclear factor (NF)-κB (C) exhibited an identical pattern amongst the four groups. * vs. other bars with different symbols, p < 0.0001. D) The protein expression of intercellular adhesion molecule (ICAM)-1. * vs. other bars with different symbols, p < 0.0001. E &F) Expression of protein carbonyls (i.e., oxidized protein), an oxidative index, in the four groups of animals [Note: Right lane and left lane shown on left lower panel (E) representing control oxidized molecular protein standard and protein molecular weight marker, respectively]. DNP = 1-3 dinitrophenylhydrazone. * vs. other bars with different symbols, p < 0.0001. a = SP control; b = CLP; c = CLP + H-ADMSCs; d = CLP + A-ADMSCs. All statistical analyses used one-way ANOVA, followed by Bonferroni multiple comparison post hoc test. Symbols (*, †, ‡, §) indicating significance (at 0.05 level). CLP = cecal ligation and puncture; Normal indicates sham procedure; H-ADMSCs = healthy adipose-derived mesenchymal stem cells; A-ADMSCs = apoptotic adipose-derived mesenchymal stem cells.Back to article page