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Figure 1 | Journal of Translational Medicine

Figure 1

From: IL-12 based gene therapy in veterinary medicine

Figure 1

Intratumoral EGT procedure in a dog with a mast cell tumor in the gluteal region. A: tumor before the procedure; B: intratumoral injection of IL-12 plasmid; C: delivery of electric pulses using plate electrodes with electric pulse generator Cliniporator® (Igea s.r.l., Italy); D: nodule immediately after the procedure. A marked paleness of the electroporated area compared to the surrounding tissue can be seen (arrow), due to transient reduction of the blood flow to the tissue, caused by occlusion of blood vessels during electroporation; E: tumor 10 days after therapy.

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