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Table 1 Hematopoietic factors produced by endothelial cells

From: Exogenous endothelial cells as accelerators of hematopoietic reconstitution

Hematopoietic factors produced by endothelial cells

Source of endothelium

Stimulant

Cytokine/CSA

Reference

Umbilical vein and HUVEC

None

Granulocyte stimulatory activity

[88]

HUVEC

Endotoxin and granulocyte contact

Granulocyte-monocyte colony stimulating activity

[79]

HUVEC

None

Granulocyte-monocyte, and erythroid colony stimulating activity

[91]

HUVEC

Muramyl peptides

Granulocyte-monocyte colony stimulating activity

[94]

HUVEC

TNF-alpha

Granulocyte-monocyte colony stimulating activity

[89]

Primary and immortalized HUVEC

IL-1

Granulocyte-monocyte colony stimulating activity

[90]

Immortalized HUVEC

None

Granulocyte-monocyte colony stimulating activity

[92]

Fat capillary endothelial cells

None

GM-CSF

[93]

HUVEC

IL-1

Erythrocyte colony stimulating activity

[95]

HUVEC

Poly (IC)

Monocyte, Granulocyte, Granulocyte-Monocyte stimulatory activity

[96]

Brain perivascular endothelial cells

None

M-CSF

[97]

HUVEC

None

Stem Cell Factor

[98]

HUVEC versus bone marrow microvessels

None

High expression of heparan sulfate proteoglycans only on bone marrow microvessels, these present SDF-1

[99]

HUVEC

None

IL-3, IL-6, Stem Cell Factor

[100]

HUVEC

IL-1

GM-CSF, G-CSF

[101]

HUVEC

None

IL-11

[102]