From: A gender-related action of IFNbeta-therapy was found in multiple sclerosis
 | Treated Patients | Untreated Patients | ||
---|---|---|---|---|
Cytokines(pg/ml) | Basic condition | Basic condition | ||
 | Men | Women | Men | Women |
IL10 | 2.13 ± 0.4 | 1.8 ± 0.2 | 1.5 ± 0.1 | 1.8 ± 0.2 |
IFNγ | 16.1 ± 5 | 11.4 ± 3.2 | 14 ± 2.3 | 19.8 ± 3.6 |
IL6 | 232 ± 227a | 10 ± 9.8a | 35.8 ± 11.5 | 12.0 ± 17.5 |
IL2 | 10.8 ± 1 | 8.7 ± 0.9 | 8.7 ± 3.5 | 9.4 ± 1.5 |
IL4 | 1.1 ± 0.2 | 1.1 ± 0.1 | 0.7 ± 0.1 | 0.7 ± 0.1 |
IL12p70 | 9.2 ± 0.9 | 9.5 ± 0.8 | 11.2 ± 1.2 | 8.4 ± 0.7 |
IL12p40 | 25.2 ± 2.6 | 21.6 ± 3 | 20.1 ± 6.5 | 20.7 ± 5.1 |
TGFβ | 7324 ± 833 | 5903 ± 458 | 10721 ± 5822 | 5758 ± 386 |
 | PHA | PHA | ||
 | Men | Women | Men | Women |
IL10 | 59.7 ± 24.9 | 23.7 ± 11.8 | 78 ± 17.4 | 49.4 ± 30.2 |
IFNγ | 1149.2 ± 570 | 740 ± 112.9b | 2238 ± 904 | 2102 ± 658b |
IL6 | 759 ± 359 | 627 ± 109.1 | 673 ± 427 | 648.1 ± 153.8 |
IL2 | 18.3 ± 5.9 | 13.9 ± 7.4 | 20.6 ± 8 | 21.3 ± 4.1 |
IL4 | 9.7 ± 5.3 | 3.6 ± 1.3 | 3.6 ± 1.1 | 1.2 ± 1.5 |
IL12p70 | 13.4 ± 2.5 | 9.9 ± 0.6 | 9.1 ± 1.5 | 9.3 ± 0.9 |
IL12p40 | 196 ± 105 | 101.7 ± 15.4 | 186 ± 82 | 86.2 ± 15.4 |
TGFβ | 7644 ± 906 | 6953 ± 583 | 16029 ± 8457 | 8612 ± 4630.1 |
 | LPS | LPS | ||
 | Men | Women | Men | Women |
IL10 | 144 ± 28.2 | 215 ± 54.7 | 181 ± 50 | 195.5 ± 48.6 |
IFNγ | 135 ± 37.9 | 71.2 ± 139.4 | 1131 ± 809.3 | 263 ± 88.5 |
IL6 | 989 ± 89 | 635.9 ± 112.5 | 795 ± 173 | 813.2 ± 123.7 |
IL2 | 15.6 ± 3.7c | 11 ± 4.4 | 7.6 ± 1.5c | 12 ± 1.6 |
IL4 | 1.54 ± 0.5 | 1.1 ± 0.1d | 0.7 ± 0.1 | 0.7 ± 0.06d |
IL12p70 | 11.5 ± 1.9 | 8.9 ± 0.8 | 9.7 ± 0.9 | 9.1 ± 0.7 |
IL12p40 | 416 ± 309 | 354.4 ± 69.5 | 1203 ± 664 | 284.2 ± 87.2 |
TGFβ | 7582 ± 832 | 7524.6 ± 3492.7e | 12669 ± 6570 | 16984 ± 4854.8e |