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Table 4 Subject characteristics and PLAUR and ChAt analysis in validation study

From: Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation

       PLAUR correlation with whole brain volume   ChAt correlation with whole brain volume
  N Gender (% F) Age mean (SD) MMSE* mean (SD) PLAUR mean (SD) ** R p ChAt mean (SD) ** R p
Controls 82 58 72.8 (7.0) 29 (1.1) 1.63 (0.9) −0.35 <0.005 0.78 (0.3) 0.34 <0.01
MCI 80 57 74.7 (6.2) 27 (2.2) 0.98 (0.7) 0.14 NS 0.75 (0.3) 0.01 NS
AD 78 69 76.2 (6.4) 21 (4.5) 0.85 (0.3) −0.2 NS 0.71 (0.3) 0.23 0.06
  1. *MMSE; Mini mental state examination - a cognitive scale (maximum score = 30) used to screen for and assess degree of severity of dementia. A score of less than 24 indicates possible dementia. A score of 10–20 suggests moderate dementia and a score above 20, mild dementia. ** arbitrary units.