Table 2 Association of high EZH2, H3K27me3, and Ki-67 scores with the risk of large tumor size and distant metastasis (NS: non-significant)
Relative Risk | 95% Confidence Interval | P value | |
|---|---|---|---|
High EZH2 score | |||
All Cases | |||
-Tumor size >5 cm | 4.09 | 1.78-9.40 | P<0.001 |
-Distant metastasis | 2.20 | 1.49-3.23 | P<0.001 |
Cases other than PDSS | |||
-Tumor size >5 cm | 4.00 | 1.63-9.82 | P=0.02 |
-Distant metastasis | 2.09 | 1.36-3.21 | P=0.02 |
High H3K27me3 score | |||
All Cases | |||
-Tumor size >5 cm | 2.25 | 1.07-4.73 | NS |
-Distant metastasis | 1.64 | 1.09-2.46 | NS |
Cases other than PDSS | |||
-Tumor size >5 cm | 1.12 | 0.20-6.17 | NS |
-Distant metastasis | 1.20 | 0.55-2.60 | NS |
High Ki-67 score | |||
All Cases | |||
-Tumor size >5 cm | 2.62 | 1.29-5.34 | P=0.04 |
-Distant metastasis | 1.71 | 1.17-2.51 | NS |
Cases other than PDSS | |||
-Tumor size >5 cm | 1.75 | 0.39-7.88 | NS |
-Distant metastasis | 0.98 | 0.24-4.03 | NS |