Table 2 Association of TOP2A and TopoIIa with HER2 status
HER2 status | Fisher’s exact p | |||||
|---|---|---|---|---|---|---|
Positive | Negative | |||||
N | % | N | % | |||
TOP2A (FISH) n=221 | Amplified | 55 | 41.0 | 0 | 0 | <0.001 |
Deleted | 21 | 15.7 | 5 | 5.7 | ||
Non-amplified | 58 | 43.3 | 82 | 94.3 | ||
TopoIIa (IHC) n=193 | Negative | 39 | 33.9 | 29 | 37.2 | 0.65 |
Positive | 76 | 66.1 | 49 | 62.8 | ||