Figure 4

ERK1/2 and p38MAPK phosphorylation in neutrophils exposed to various oxygen conditions. (A) The average (± SD) normalized values of p-ERK1/2 (n=6), obtained by densitometric analysis of western blots, are presented as fold increase over β-actin in arbitrary units in normoxia (Nox), intermittent hypoxia (IH) and sustained hypoxia (SH). (B) A representative western blot depicts the dual phosphorylated (Thr202/Tyr204) form of ERK1/2 (p-ERK1/2) and dual phosphorylated (Thr180/Tyr182) form of p38MAPK (p-p38) compared to non-phosphorylated ERK1/2 and p38MAPK in Nox, IH, and SH.