Figure 6
FoxM1 siRNA decreased migration and invasion of Caki-1 and 786-O cells, and reduced the HUVECs tube formation. A , Scratch migration assay showing that FoxM1 siRNA decreased cell migration. B , Matrigel invasion assay showing that FoxM1 siRNA-transfected cells resulted in low penetration through the Matrigel-coated membrane, compared with control cells. C , Conditioned media from FoxM1 siRNA-transfected cells were able to significantly reduce the tube formation of HUVECs compared with the medium from control cells. The experiments were repeated thrice. **, P < 0.01, relative to control.