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Table 4 Univariate and multivariate Cox regression analysis for overall survival in patients with ESCC

From: Preoperative Cyfra21-1 and SCC-Ag serum titers predict survival in patients with stage II esophageal squamous cell carcinoma

 

Univariate analysis

Multivariate analysis

Characteristics

HR

95% CI

P value*

HR

95% CI

P value*

Age, years

1.014

1.001 to 1.028

0.038

0.998

0.985-1.012

0.764

Sex

      

 Male vs. Female

1.212

0.902 to 1.629

0.202

-

-

-

Tumor location

      

 Upper vs. Middle vs. Lower

0.980

0.558 to 1,611

0.318

-

-

-

Tumor Grade

      

 Grade 1 vs. 2 vs. 3

1.668

1.085 to 2.166

0.056

-

-

-

pTNM stage

      

 Stage IIA vs. Stage IIB

2.283

1.600 to 3.257

<0.001

2.191

1.533 to 3.132

<0.001

Cyfra21-1 level

      

 Low vs. High

7.439

5.178 to 10.686

<0.001

7.149

4.961 to 10.303

<0.001

SCC-Ag level

      

 Low vs. High

3.940

2.229 to 6.964

<0.001

2.926

1.655 to 5.175

<0.001

  1. Abbreviation: HR, hazard ratio; 95% CI, 95% confidence interval; pTNM stage, pathological tumor-node-metastasis stage.
  2. * Cox proportional hazards model.
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Journal of Translational Medicine

ISSN: 1479-5876

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