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Table 3 Prognostic value of preoperative Cyfra21-1 and SCC-Ag level in ESCC patients

From: Preoperative Cyfra21-1 and SCC-Ag serum titers predict survival in patients with stage II esophageal squamous cell carcinoma

Biomarker

Cyfra21-1

SCC-Ag

Level

No.

Median OS

5-year survival

P value*

No.

Median OS

5-year survival

P value*

Total

   

<0.001

   

<0.001

 Low

198

91.9

85%

 

103

89.7

82%

 

 High

181

46.6

33%

 

276

63.7

53%

 

pTNM stage

        

 Stage IIA

   

<0.001

   

0.069

  Low

75

102.6

93%

 

46

85.7

86%

 

  High

52

59.9

54%

 

81

78.2

72%

 

Stage IIB

   

<0.001

   

<0.001

  Low

123

84.4

80%

 

57

73.7

78%

 

  High

129

41.1

25%

 

195

57.1

45%

 
  1. Abbreviation: pTNM stage, pathological tumor-node-metastasis stage.
  2. * Log-rank test.