Table 4 Frequencies of somatic mutations in the series of 384 patients screened for all three genes, according to the geographical origin
Patients’ origin | KRAS |  |  | PIK3CA | wild-type |
|---|---|---|---|---|---|
|  |  | KRAS + PIK3CA | BRAF + PIK3CA |  |  |
| Â | % | % | % | % | % |
North Sardinia (N = 183) | 66 | 8 | 0 | 11 | 98 |
36.1 | 4.4 | 0 | 6.0 | 53.5 | |
Middle-South Sardinia (N = 201) | 41 | 7 | 1 | 40 | 112 |
20.4 | 3.5 | 0.5 | 19.9 | 55.7 | |
Total (N = 384) | 107 | 15 | 1 | 51 | 210 |
| Â | 27.8 | 3.9 | 0.3 | 13.3 | 54.7 |