Figure 3
Cell lines predict tumor behavior, comparing AA vs GG. K mean clustering method organize heat map of melanoma metastases re-clustered based on 106 genes differentiating melanoma cell lines with distinct IRF5 genotype. On the right side of the panel, a subset of metastases significantly enriched in non-responders; on the left side of the panel, a set of cases that enriched in responders (Fisher test: p2-value = 0.025).