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Figure 10 | Journal of Translational Medicine

Figure 10

From: Combination of cilostazol and clopidogrel attenuates Rat critical limb ischemia

Figure 10

Proposed mechanisms underlying the effects of different treatment on CLI in a rat model based on the findings of the present study. EPC = endothelial progenitor cell; eNOS = endothelial nitric oxide synthase; vWF = von Willebrand factor; PGC-1α = peroxisome proliferator-activated receptor-γ coactivator-1α; Cyt C = cytochrome C; PARP = poly(ADP-ribose) polymerase; MMP-9 = matrix metalloproteinase; PAI-1 = plasminogen activator inhibitor 1; TNF-α = tumor necrotic factor-α; IL-10 = interleukin-10; VCAM-1 = vascular cell adhesion molecule 1; miRNA = microRNA; INBF = ratio of ischemic to normal blood flow.

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